That screen you see there is the 'remote control' screen to allow 1 orbiter to be a remote keyboard/mouse for another. Here's how it works....
If I'm using an orbiter, like a webpad, and I choose a computing application, that orbiter (the webpad/pda, etc.) turns into a remote keyboard/mouse for whatever media director I'm running the application on. When you type on that keyboard, those keystrokes get fed to the computing application. When you touch around in that white box, that moves the mouse around on that computing application.
If instead of using a remote orbiter, I go directly to the media director itself, and choose a computing application, you should not see that screen--rather you see the computing application itself. Use the keyboard/mouse like normal.
The only time you will ever see that screen on a media director is if, on the main menu, you change the room. Let's say the media director you are using is in the living room. And on the main menu you choose another room, dining room. Now when you choose a computing application using the media director in the living room, because it is controlling the dining room, the computing application gets launched in the dining room and the media director in the living room shows that screen because it is now a remote control for the dining room. You are now remotely controlling the dining room from the living room. Normally people don't do that.
If you're getting this screen on a media director, one possibility is that you put 2 media directors in the same room. This is a no-no. The reason is that we designed media to be 'exclusive' to a room to make it simpler for the user. For example, with a traditional remote control if I start listening to a cd and then decide I want to watch tv, I have to remember to first turn the cd player off, and maybe create some macros. Pluto uses a different approach which has no macros. It assumes you only have 1 media playing at a time in a room, so it automatically knows to stop other media devices. There is a way around this by using the 'manually configure entertainment areas' option inside rooms. But, we don't recommend this since it makes it more complicated to setup and 99% of the time people only have 1 media playing in a room at a time. So when you leave Pluto with the default settings, the architecture is designed so that in each room you only have 1 media director, and all media is exclusive within this room.
If you follow this, the behavior you see should be intuitive. In other words, if I have a touch-screen pda, I walk into the living room, tell the pda I'm in the living room with the room button, and then hit 'computing' and choose a web site, the TV in that room will come on automatically, the web site appears on the TV, and the pda becomes a remote keyboard/mouse to control that TV, or I can use the keyboard/mouse connected to the media director. On the pda you can then chose another room, start an email browser, and the pda becomes a remote control for that email browser. When you change back to the first room it goes back to being a remote control for the web browser. And in the case of the mobile phone it's automatic since the phone detects its location automatically. You walk into the living room and the phone is a remote control for whatever you're doing in the room; if you're watching TV, the up/down/left/right rocker on the phone changes channels, if you're listening to a CD, it changes tracks, and if you're browsing a web page, it moves the mouse. Move into another room and it automatically switches to controlling whatever it is you're doing in that room.
I know the logic of it sounds complex, but normally nobody thinks about it since the end behavior is what people would intuitively expect. Something is wrong with your configuration if you're getting weird behavior like you describe. And the only 2 odd things I've seen people do that causes unexpected behavior is 1) put 2 media directors in the same room--then Pluto cannot reliably figure out which one you want to control or 2) on the media director itself change the room by clicking the 'room' button on the on-screen display's main menu, which causes that media director to become a remote control for the other room--rather than controlling it's own room.