There isn't much. basically just a few paths, and a DSN. Getting it to run under wine may be a problem because of the use of ODBC.
However, I _can_ tell you, that HADesigner _DOES_ run under Mono, but some things need to be fixed (particularly in regards to implementation differences in transaction handling between the old Microsoft.Data.Odbc and the ECMA'd System.Data.Odbc.)
So maybe you wanna take a crack at that?