you can copy that file to the /etc/modprobe.d/ directory in your Pluto system they should be in effect, with the exception of the lirc modules. You can copy just the "options" lines. Then, when you reboot your system/reload the concerning modules, the new settings should come into effect.
Knoppmyth has a file "Knoppmyth" in /etc/modutils.d or /etc/modprobe.d (onea is a legacy holdback basically). In /etc/mythtv/modules they have files like:
which contain the appropriate configurations for those cards (e.g. alias char-major 81 videodev, options bttv tuner=49, etc). Knoppmyth then figures out your configuration by looking at lspci and then imports the appropriate files. e.g. for my config, one PVR-150 and a Kworld BTTV card,
If you only have bttv cards then you'll include the bttv file first, otherwise if you have any ivtv cards it will include the ivtv file first.
ivtv0 makes the PVR 150 identified as /dev/video0 and
bttv1 makes the KWorld bttv /dev/video1.
SO. Frankly, if you have access to a Knoppmyth system, I'd say copy those files and use them. I'm not sure what script makes the Knoppmyth file, though. You could just do it by hand though.