Personally I have never known it (except for when the drive is knackered!)
I am a fan of the slimline slot-loading (not the tray type) DVD drives. I have used both SATA and USB DVD drives (same drive, just that one of them is in a USB caddy off eBay) and they work fine.
The USB one is being used on my carPC, which is a CLI Ubuntu, no problems there (except when trying to boot off a CD/DVD, I assume that's because it's USB). No problems with the SATA one either, that one is attached to the back of my TV with a little bracket.
Where is the mobo in question currently? Behind the TV? There are various miniITX cases that accommodate slimline slot-loading drives. I won't post any links as they will also be in the UK.
EDIT: Had an idea for the USB caddy, think I might do this myself. The caddy comes in two halves - drill four small holes in one of the halves and screw to wall (or wherever) with some very small countersunk screws. Install DVD drive. Clip other half of cover in place. Job done!