Getting skype audio integration into Asterisk doesn't seem to be a problem and probably worth the cost of the commercial solution if that's all you want. In my case, I want video-enabled skype-to-skype calling from a media center. Looking at the
skype API for linux, it still seems that GET / SET VIDEO_IN interface is still missing. Looks like this needs to wait until the API is more complete which is inevitable when the open-source the client.
In the time spent waiting for the video interface, you could get the audio and contacts interfaces working for you... I'm guessing there is probably quite a bit of work in those areas to begin with...