I know it works with the Gyration go-mouse. The 3 soft buttons are the same and map to f6,f7,f8. And it works with that custom remote in the video. I looked at the photos of the Gyration windows mouse and it appears that it doesn't have those same 3 soft buttons. The left and right are left click/right click. Which in Ui2 is ok and cancel, not media & ambiance. So I'm not sure what it woudl take to get the MCE Windows remote to work, or even if it is possible. I've never tried it, but from what I can tell the remote in the demo video uses the same plastic mold as the windows mce remote, but the way they function appears to be totally different.